Lantheus Holdings, Inc.
Rank #143HypergrowthLNTH · Nasdaq · Healthcare
Lantheus Holdings, Inc. (LNTH) — Rank #143 by gross profitability (GP/assets 0.39) · ROE 17.8% · Piotroski F-Score N/A.
As-of 2026-09-15 · CIK 0001521036 · all metrics point-in-time as of the filing date.
About
Lantheus Holdings, Inc. develops, manufactures, and commercializes diagnostic and therapeutic products that assist clinicians in diagnosis and treatment of heart, cancer, and other diseases worldwide.
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The company offers DEFINITY, an injectable ultrasound enhancing agent used in echocardiography exams; TechneLite, a technetium generator for nuclear medicine procedures; Xenon-133, a radiopharmaceutical gas to assess pulmonary function; Neurolite, an injectable imaging agent to identify the area within the brain where blood flow has been blocked or reduced due to stroke; Cardiolite, an injectable Tc-99m-labeled imaging agent to assess blood flow to the muscle of the heart; and PYLARIFY, an F 18-labelled PSMA-targeted PET imaging agent used for imaging of PSMA positive-lesions in men with prostate cancer. It also provides Automated Bone Scan Index that calculates the disease burden of prostate cancer by detecting and classifying bone scan tracer uptakes as metastatic or benign lesions using an artificial neural network; RELISTOR for opioid-induced constipation; and aPROMISE, an artificial intelligence medical device software; PYLARIFY AI, an medical device software to perform quantitative assessment of PSMA PET/CT images in prostate cancer; and flurpiridaz used to assess blood flow to the heart. In addition, it develops PNT2002, a radiopharmaceutical therapy to treat mCRPC; PNT2003, an SSTR therapy to patients with SSTR-positive neuroendocrine tumors; MK-6240, a F 18-labeled PET imaging agent for Tau tangles in Alzheimer's disease; LNTH-2401, a novel radiodiagnostic targeting the gastrin-releasing peptide receptor; LNTH-2402; LNTH-2403; LNTH-2404; LNTH-250; LNTH-2515; and LNTH-1363S, an fibroblast activation protein, alpha, copper-64 labeled PET imaging agent. It has collaboration agreements with GE Healthcare; Curium Pharma; POINT; Regeneron; and Ratio Therapeutics LLC.
The company was founded in 1956 and is based in Bedford, Massachusetts.
- Industry
- Drug Manufacturers - Specialty & Generic
- Sector
- Healthcare
- State
- DE
- Filer Category
- Large accelerated filer
- Fiscal Year End
- December 31
- Website
- lantheus.com
Price History
Company Snapshot
P/S is the primary valuation lens — earnings are reinvested, not available for P/E.
Market Cap
$6.56B
P/E (annual)
29.5
P/S (annual)
4.3
P/B
5.0
P/OCF (annual)
16.8
Shareholder Yield
-76.0%
Employees
1,193
Industry
Drug Manufacturers - Specialty & Generic
Exchange
Nasdaq
Signal Flags
Quality Profile
Profitability
1/1 passSafety
1/1 passCash Flow
3/3 passGrowth
1/2 passTerry Smith quality gate
Passes 3/5 Terry Smith thresholds1 of 5 threshold not computable from filed data.
What Growth Is Priced In
Implied revenue growth (10Y)
6.0%
The annual FCF growth rate today's price requires over a 10-year horizon (discount rate 10%, terminal growth 2.5%).
Dilution drag: 76.0% — per-share value needs a total required return of 82.0% once share-count change is priced in.
vs. own 6-year median revenue growth: 0.1%
priced above its own historyCost-of-equity sensitivity (implied growth at different discount rates)
r = 8%
1.8%
r = 10% (base)
6.0%
r = 12%
9.6%
Net debt / market cap: -8.6%
Valuation History
Current multiple vs historical range at each filing date. Band spans 25th-75th percentile.
P / E
Price / diluted EPS
P / S
Price / revenue per share
P / B
Price / book value per share
P / GP
Price / gross profit per share
P / FCF
Price / free cash flow per share
Disclosure regression check
A previously-disclosed line item is no longer reported. Worth checking the filing for why.
Revenue growth and the path to profitability (margin trend) are the primary reads at this stage.
Profitability
Gross profitability (GP / assets)
0.39
Primary signal (Novy-Marx).
79th pctl of 34 SIC 28 peers
Return on equity
17.8%
Gross margin
61.1%
61st pctl of 34 SIC 28 peers
Revenue growth (YoY)
365.2%
Gross margin improving
Margin trend vs prior year.
Operating Leverage
| 2015 | 2016 | 2017 | 2018 | |
|---|---|---|---|---|
| Revenue vs COGS | ||||
| Revenue vs OpEx | ||||
| Op. Income vs Revenue |
Growth
Revenue CAGR (3Y)
—
Revenue CAGR (5Y)
—
Earnings CAGR (3Y)
102.6%
FCF CAGR (3Y)
—
Anti-fragile safety
Balance-sheet safety
Composite anti-fragile check.
Debt / equity
0.84
47th pctl of 31 SIC 28 peers (best = lowest)
Current ratio
3.06×
70th pctl of 34 SIC 28 peers
Quick ratio
2.82×
Net cash
$592.60M
Cash & equivalents minus total debt.
Cash-flow health
Free cash flow
$390.14M
Operating cash flow minus capex.
Positive free cash flow
FCF / net income
0.67
Cash-backing of earnings.
FCF/NI divergence
Unfavorable divergence (yellow flag).
Accruals healthy
Cash-backed earnings.
SBC / revenue
5.6%
Stock-based comp intensity.
Piotroski F-Score
F-Score
N/A
Only 8/9 components determinable.