BioCryst Pharmaceuticals, Inc.
Rank #3HypergrowthBCRX · Nasdaq · Healthcare
BioCryst Pharmaceuticals, Inc. (BCRX) — Rank #3 by gross profitability (GP/assets 1.53) · ROE -58.1% · Piotroski F-Score 8 / 9.
As-of 2026-09-15 · CIK 0000882796 · all metrics point-in-time as of the filing date.
About
BioCryst Pharmaceuticals, Inc., a biotechnology company, developing and commercializing medicines for hereditary angioedema (HAE) and other rare diseases.
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The company markets peramivir injection, an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated and seasonal influenza under the RAPIVAB, RAPIACTA, and PERAMIFLU names; and ORLADEYO, an oral serine protease inhibitor to treat HAE. It is also developing BCX17725, a protein therapeutic for netherton syndrome which is in phase 1; Avoralstat, an ocular plasma kallikrein inhibitor for diabetic macular edema that is in Phase 1; Navenibart, a monoclonal antibody plasma kallikrein inhibitor for HAE which is in Phase 3; BCX17725, an investigational protein therapeutic KLK5 inhibitor for the treatment of netherton syndrome that is in phase 1 clinical trial; STAR-0310, a monoclonal antibody OX40 antagonist for the treatment of atopic dermatitis which is in Phase 1a trial. The company has collaborations and in-license relationships with the Torii Pharmaceutical Co., Ltd., Shionogi & Co., Ltd., and Green Cross Corporation; National Institute of Allergy and Infectious Diseases; Biomedical Advanced Research and Development Authority; the U.S. Department of Health and Human Services; and Albert Einstein College of Medicine of Yeshiva University and Industrial Research, Ltd. BioCryst Pharmaceuticals, Inc.
was founded in 1986 and is headquartered in Durham, North Carolina.
- Industry
- Drug Manufacturers - Specialty & Generic
- Sector
- Healthcare
- State
- DE
- Filer Category
- Large accelerated filer
- Fiscal Year End
- December 31
- Website
- biocryst.com
Financials
Each fiscal year is read as-of that year’s own 10-K filing, so nothing restated after the fact leaks backwards. Line items this filer never tagged are omitted. Hover or tap a badge for the diagnostic behind it.
| Fiscal year end | 2017-12-31filed 2018-03-12 | 2016-12-31filed 2017-02-27 | 2015-12-31filed 2016-02-26 | 2014-12-31filed 2015-03-02 |
|---|---|---|---|---|
| Revenue | 25.2 | 26.4 | 48.3 | 13.6 |
| Revenue growth (YoY) | -4.4% | -45.4% | 254.6% | -21.5% |
| Cost of revenue | 1.1 | 2.3 | 1.4 | 0.0 |
| Gross profit | 24.0 | 24.1 | 46.9 | 13.6 |
| Gross margin | 95.5% | 91.3% | 97.2% | 100.0% |
| Selling, general & administrative | 13.9 | 11.3 | 13.0 | — |
| Research & development | 67.0 | 61.0 | 72.8 | 51.8 |
| Operating income | (57.4) | (48.6) | (39.4) | (45.8) |
| Operating margin | -227.9% | -184.4% | -81.7% | -336.4% |
| Interest expense | 8.6 | 6.5 | 5.2 | 5.0 |
| Income tax expense | 0.0 | — | — | 17.3 |
| Net income | (65.8) | (55.1) | (43.0) | (45.2) |
| Net margin | -261.2% | -209.3% | -89.1% | -332.1% |
Figures are as originally filed with the SEC (point-in-time), not restated, so they can differ slightly from sites that show later-restated numbers. Why point-in-time?